Upstream Bio, Inc. Common Stock(UPB:US)
Market Cap$150.2M
Key Metrics
Price$2.76
Revenue (TTM)$3.32M
Holders Revenue (TTM)-
Gross Profit (TTM)-
Earnings (TTM)-$156.76M
EBITDA (TTM)-$171.77M
Op. Margin (TTM)-5.18K%
Dividend Yield-
Holders Yield-
Cash on hand$96.72M
Total Assets$318.05M
Net Assets$304M
Total Debt$1.11M
Key Metrics
Price$2.76
Revenue (TTM)$3.32M
Holders Revenue (TTM)-
Gross Profit (TTM)-
Earnings (TTM)-$156.76M
EBITDA (TTM)-$171.77M
Op. Margin (TTM)-5.18K%
Dividend Yield-
Holders Yield-
Cash on hand$96.72M
Total Assets$318.05M
Net Assets$304M
Total Debt$1.11M
Financials

| Name | Mar 31, 2026 | Dec 31, 2025 | Sep 30, 2025 | Jun 30, 2025 | Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Dec 31, 2023 | Sep 30, 2023 |
|---|---|---|---|---|---|---|---|---|---|---|
Revenue | $1.03M | $668K | $683K | $937K | $566K | $613K | $607K | $510K | $450K | $621K |
Cost of Revenue | - | - | - | - | - | - | - | - | - | - |
Gross Profit | - | - | - | - | - | - | - | - | - | - |
| $44.65M | $46.84M | $38.52M | $45.28M | $32.58M | $26.93M | $19.5M | $18.05M | $14.78M | $10.01M | |
| Research and Development | $36.57M | $40.17M | $32.98M | $37.87M | $25.8M | $21.77M | $15.43M | $14.07M | $11.55M | $7.79M |
| Selling, General, and Administrative | $8.08M | $6.67M | $5.54M | $7.42M | $6.78M | $5.16M | $4.07M | $3.98M | $3.23M | $2.22M |
| Other Operating Expenses | - | - | - | - | - | - | - | - | - | - |
Operating Income | -$43.62M | -$46.17M | -$37.83M | -$44.35M | -$32.01M | -$26.32M | -$18.89M | -$17.54M | -$14.33M | -$9.39M |
| $3.02M | $3.71M | $4.09M | $4.38M | $4.74M | $5.08M | $2.9M | $2.86M | $2.5M | $6.28M | |
| Non-Operating Interest Income | $3.05M | $3.65M | $4.11M | $4.43M | $4.74M | $5.08M | $2.9M | $2.88M | $1.52M | $1.53M |
| Non-Operating Interest Expense | - | - | - | - | - | - | - | - | - | - |
| Other Income/Expense | -$30K | $54K | -$19K | -$50K | - | $0 | -$3K | -$15K | $978K | $4.76M |
Income Before Tax | -$40.59M | -$42.46M | -$33.75M | -$39.97M | -$27.27M | -$21.24M | -$15.99M | -$14.68M | -$11.83M | -$3.1M |
Income Tax | - | - | - | - | - | - | - | - | - | - |
Net Income | -$40.59M | -$42.46M | -$33.75M | -$39.97M | -$27.27M | -$21.24M | -$15.99M | -$14.68M | -$11.83M | -$3.1M |
Minority Interests | - | - | - | - | - | - | - | - | - | - |
Preferred Stock Dividends | - | - | - | - | - | - | - | - | - | - |
Net Income to Common | -$40.59M | -$42.46M | -$33.75M | -$39.97M | -$27.27M | -$21.24M | -$15.99M | -$14.68M | -$11.83M | -$3.1M |
Shares Outstanding (Basic) | 54.42M | 54.24M | 53.93M | 53.8M | 53.64M | 53.6M | 51.34M | - | - | 36.32M |
Shares Outstanding (Diluted) | 54.42M | 54.24M | 53.93M | 53.8M | 53.64M | 53.6M | 51.34M | - | - | 36.32M |
EPS (Basic) | -$0.75 | -$0.78 | -$0.63 | -$0.74 | -$0.51 | -$0.40 | -$0.41 | - | - | -$0.17 |
EPS (Diluted) | -$0.75 | -$0.78 | -$0.63 | -$0.74 | -$0.51 | -$0.40 | -$0.41 | - | - | -$0.17 |
EBIT | -$43.62M | -$46.17M | -$37.83M | -$44.35M | -$32.01M | -$26.32M | -$18.89M | -$17.54M | -$14.33M | -$9.39M |
EBITDA | -$43.57M | -$46.11M | -$37.79M | -$44.31M | -$31.97M | -$26.27M | -$18.88M | -$17.53M | -$14.32M | -$9.37M |
