Spyre Therapeutics, Inc.(SYRE:US)
Market Cap$6.299B
Key Metrics
Price$79.90
Revenue (TTM)$0
Holders Revenue (TTM)$0
Gross Profit (TTM)-
Earnings (TTM)-$179.44M
EBITDA (TTM)-$281.64M
Op. Margin (TTM)-
Dividend Yield-
Holders Yield-
Cash on hand$97.19M
Total Assets$763.95M
Net Assets$670.81M
Total Debt$0
Key Metrics
Price$79.90
Revenue (TTM)$0
Holders Revenue (TTM)$0
Gross Profit (TTM)-
Earnings (TTM)-$179.44M
EBITDA (TTM)-$281.64M
Op. Margin (TTM)-
Dividend Yield-
Holders Yield-
Cash on hand$97.19M
Total Assets$763.95M
Net Assets$670.81M
Total Debt$0
Financials

| Name | Mar 31, 2026 | Dec 31, 2025 | Sep 30, 2025 | Jun 30, 2025 | Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jun 30, 2022 | Mar 31, 2022 | Dec 31, 2021 | Sep 30, 2021 | Jun 30, 2021 | Mar 31, 2021 | Dec 31, 2020 | Sep 30, 2020 | Jun 30, 2020 | Mar 31, 2020 | Dec 31, 2019 | Sep 30, 2019 | Jun 30, 2019 | Mar 31, 2019 | Dec 31, 2018 | Sep 30, 2018 | Jun 30, 2018 | Mar 31, 2018 | Dec 31, 2017 | Sep 30, 2017 | Jun 30, 2017 | Mar 31, 2017 | Dec 31, 2016 | Sep 30, 2016 | Jun 30, 2016 | Mar 31, 2016 | Dec 31, 2015 | Sep 30, 2015 | Jun 30, 2015 | Mar 31, 2015 | Dec 31, 2014 | Sep 30, 2014 | Jun 30, 2014 | Mar 31, 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Revenue | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $688K | $198K | $168K | $174K | $625K | $1.36M | $3.64M | $1.4M | $13.7M | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $2.38M | $1.51M | $1.48M | $1.26M | $1.48M | $982K | $1.25M | $1.15M | $1.37M | $859K | $1.59M | $1.07M | $3.43M | $0 | $0 | $0 | $0 | $0 |
Cost of Revenue | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Gross Profit | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| $75.64M | $57.17M | $56.89M | $51.94M | $53.57M | $61.25M | $55.39M | $44.15M | $47.77M | $47.75M | $33.24M | $29.45M | $19M | $19.33M | $18.93M | $23.05M | $25.8M | $24.09M | $21.69M | $20.4M | $18.21M | $22.78M | $18.12M | $21.56M | $19.02M | $21.91M | $22.15M | $18.62M | $17.66M | $15.31M | $12.24M | $12.05M | $9.76M | $8.11M | $9.26M | $8.2M | $7.31M | $6.79M | $7.45M | $6.87M | $5.43M | $5.58M | $4.49M | $4.86M | $2.47M | $3.18M | $3.14M | $1.73M | $857K | |
| Research and Development | $60.41M | $44.64M | $45.25M | $40.15M | $41.62M | $50.48M | $44.74M | $32.64M | $34.93M | $33.68M | $24.66M | $17.39M | $13.78M | $14.25M | $11.98M | $15.37M | $16.98M | $16.78M | $14.85M | $13.58M | $11.86M | $15.76M | $12.45M | $16.87M | $14.56M | $17.57M | $17.84M | $14.81M | $14.39M | $11.8M | $8.93M | $9.12M | $6.87M | $5.79M | $6.24M | $5.84M | $4.95M | $4.74M | $5.39M | $4.42M | $3.6M | $3.97M | $3.13M | $2.74M | $1.62M | $2.55M | $2.49M | $1.26M | $533K |
| Selling, General, and Administrative | $15.23M | $12.53M | $11.64M | $11.79M | $11.94M | $10.77M | $10.65M | $11.51M | $12.85M | $14.07M | $8.58M | $12.06M | $5.23M | $5.08M | $6.95M | $7.68M | $8.83M | $7.3M | $6.84M | $6.82M | $6.35M | $7.02M | $5.67M | $4.69M | $4.46M | $4.34M | $4.31M | $3.82M | $3.27M | $3.51M | $3.31M | $2.93M | $2.89M | $2.32M | $3.02M | $2.36M | $2.36M | $2.05M | $2.07M | $2.45M | $1.83M | $1.62M | $1.36M | $2.12M | $847K | $628K | $653K | $469K | $324K |
| Other Operating Expenses | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Operating Income | -$75.64M | -$57.17M | -$56.89M | -$51.94M | -$53.57M | -$61.25M | -$55.39M | -$44.15M | -$47.77M | -$47.75M | -$33.24M | -$28.76M | -$18.81M | -$19.16M | -$18.76M | -$22.42M | -$24.44M | -$20.44M | -$20.29M | -$6.71M | -$18.21M | -$22.78M | -$18.12M | -$21.56M | -$19.02M | -$21.91M | -$22.15M | -$18.62M | -$17.66M | -$15.31M | -$12.24M | -$9.67M | -$8.25M | -$6.63M | -$8M | -$6.72M | -$6.33M | -$5.54M | -$6.3M | -$5.5M | -$4.57M | -$4M | -$3.42M | -$1.43M | -$2.47M | -$3.18M | -$3.14M | -$1.73M | -$857K |
| $6.64M | -$5.36M | $45.71M | $15.22M | $8.78M | $4.96M | -$13.62M | $5.31M | $3.95M | -$15.43M | -$6.86M | -$188.31M | $348K | $378K | $312K | $109K | $5K | $19K | $12K | -$33K | -$9K | $62K | $90K | $142K | $294K | $414K | $573K | $603K | $490K | $407K | $326K | $256K | $126K | $143K | $124K | $88K | $84K | $60K | $63K | $65K | $20K | $10K | $4K | $5K | $1K | $0 | -$110K | -$670K | -$663K | |
| Non-Operating Interest Income | $7M | $7.14M | $5.38M | $5.87M | $6.49M | $5.78M | $5.18M | $5.92M | $4.43M | $4.13M | $1.25M | $350K | $420K | $410K | $288K | $104K | $35K | $34K | $36K | $19K | $22K | $44K | $88K | $161K | $300K | $432K | $585K | $619K | $507K | $427K | $339K | $263K | $143K | $150K | $136K | $100K | $95K | $72K | $72K | $74K | $26K | $11K | $5K | $5K | $1K | $0 | $1K | $0 | $0 |
| Non-Operating Interest Expense | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Other Income/Expense | -$359K | -$12.5M | $40.33M | $9.34M | $2.29M | -$818K | -$18.8M | -$610K | -$483K | -$19.55M | -$8.11M | -$188.66M | -$72K | -$32K | $24K | $5K | -$30K | -$15K | -$24K | -$52K | -$31K | $18K | $2K | -$19K | -$6K | -$18K | -$12K | -$16K | -$17K | -$20K | -$13K | -$7K | -$17K | -$7K | -$12K | -$12K | -$11K | -$12K | -$9K | -$9K | -$6K | -$1K | -$1K | - | - | $0 | -$111K | -$670K | -$663K |
Income Before Tax | -$69.01M | -$62.53M | -$11.18M | -$36.72M | -$44.79M | -$56.3M | -$69.01M | -$38.84M | -$43.83M | -$63.18M | -$40.1M | -$217.07M | -$18.46M | -$18.78M | -$18.44M | -$22.31M | -$24.44M | -$20.42M | -$20.28M | -$6.74M | -$18.22M | -$22.71M | -$18.03M | -$21.42M | -$18.73M | -$21.5M | -$21.57M | -$18.02M | -$17.17M | -$14.9M | -$11.92M | -$9.41M | -$8.12M | -$6.48M | -$7.87M | -$6.63M | -$6.25M | -$5.48M | -$6.24M | -$5.43M | -$4.55M | -$3.99M | -$3.41M | -$1.43M | -$2.47M | -$3.18M | -$3.25M | -$2.4M | -$1.52M |
Income Tax | $0 | $0 | $0 | $0 | -$15K | $1K | $18K | $0 | $32K | $0 | $3K | $7K | -$36K | $38K | -$209K | $9K | $0 | $23K | $26K | $92K | - | - | $0 | $0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Net Income | -$69.01M | -$62.53M | -$11.18M | -$36.72M | -$44.77M | -$56.3M | -$69.03M | -$38.84M | -$43.86M | -$63.18M | -$40.11M | -$217.08M | -$18.42M | -$18.82M | -$18.23M | -$22.32M | -$24.44M | -$20.45M | -$20.31M | -$6.83M | -$18.22M | -$22.71M | -$18.03M | -$21.42M | -$18.73M | -$21.5M | -$21.57M | -$18.02M | -$17.17M | -$14.9M | -$11.92M | -$9.41M | -$8.12M | -$6.48M | -$7.87M | -$6.63M | -$6.25M | -$5.48M | -$6.24M | -$5.43M | -$4.55M | -$3.99M | -$3.41M | -$1.43M | -$2.47M | -$3.18M | -$3.25M | -$2.4M | -$1.52M |
Minority Interests | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Preferred Stock Dividends | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Net Income to Common | -$69.01M | -$62.53M | -$11.18M | -$36.72M | -$44.77M | -$56.3M | -$69.03M | -$38.84M | -$43.86M | -$63.18M | -$40.11M | -$217.08M | -$18.42M | -$18.82M | -$18.23M | -$22.32M | -$24.44M | -$20.45M | -$20.31M | -$6.83M | -$18.22M | -$22.71M | -$18.03M | -$21.42M | -$18.73M | -$21.5M | -$21.57M | -$18.02M | -$17.17M | -$14.9M | -$11.92M | -$9.41M | -$8.12M | -$6.48M | -$7.87M | -$6.63M | -$6.25M | -$5.48M | -$6.24M | -$5.43M | -$4.55M | -$3.99M | -$3.41M | -$1.43M | -$2.47M | -$3.18M | -$3.25M | -$2.4M | -$1.52M |
Shares Outstanding (Basic) | 78.55M | 75.09M | 60.78M | 60.7M | 60.27M | 55.26M | 50.89M | 45.32M | 36.51M | - | 4.29M | 3.82M | 3.77M | - | 3.77M | 3.29M | 2.64M | - | 2.63M | 2.63M | 2.62M | - | 2.49M | 2.12M | 1.32M | - | 1.32M | 1.31M | 1.16M | - | 879.48K | 823.95K | 666.89K | - | 656.39K | 564.56K | 534.63K | - | 533.04K | 471.04K | 457.19K | - | 272.8K | 272.8K | 272.8K | - | - | - | 272.8K |
Shares Outstanding (Diluted) | 78.55M | 75.09M | 60.78M | 60.7M | 60.27M | 55.26M | 50.89M | 45.32M | 36.51M | - | 4.29M | 3.82M | 3.77M | - | 3.77M | 3.29M | 2.64M | - | 2.63M | 2.63M | 2.62M | - | 2.49M | 2.12M | 1.32M | - | 1.32M | 1.31M | 1.16M | - | 879.48K | 823.95K | 666.89K | - | 656.39K | 564.56K | 534.63K | - | 533.04K | 471.04K | 457.19K | - | 272.8K | 272.8K | 272.8K | - | - | - | 272.8K |
EPS (Basic) | -$0.74 | -$0.70 | -$0.18 | -$0.60 | -$0.60 | -$0.81 | -$1.06 | -$0.59 | -$0.72 | - | -$0.86 | -$40.14 | -$5 | - | -$4.84 | -$6.75 | -$9.25 | - | -$7.75 | -$2.50 | -$7 | - | -$7.25 | -$10 | -$14.25 | - | -$16.50 | -$13.75 | -$14.75 | - | -$13.50 | -$11.50 | -$12.25 | - | -$12 | -$11.75 | -$11.75 | - | -$11.75 | -$11.50 | -$9.95 | - | -$12.51 | -$5.23 | -$9.88 | - | - | - | -$5.57 |
EPS (Diluted) | -$0.74 | -$0.70 | -$0.18 | -$0.60 | -$0.60 | -$0.81 | -$1.06 | -$0.59 | -$0.72 | - | -$0.86 | -$40.14 | -$5 | - | -$4.84 | -$6.75 | -$9.25 | - | -$7.75 | -$2.50 | -$7 | - | -$7.25 | -$10 | -$14.25 | - | -$16.50 | -$13.75 | -$14.75 | - | -$13.50 | -$11.50 | -$12.25 | - | -$12 | -$11.75 | -$11.75 | - | -$11.75 | -$11.50 | -$9.95 | - | -$12.51 | -$5.23 | -$9.88 | - | - | - | -$5.57 |
EBIT | -$75.64M | -$57.17M | -$56.89M | -$51.94M | -$53.57M | -$61.25M | -$55.39M | -$44.15M | -$47.77M | -$47.75M | -$33.24M | -$28.76M | -$18.81M | -$19.16M | -$18.76M | -$22.42M | -$24.44M | -$20.44M | -$20.29M | -$6.71M | -$18.21M | -$22.78M | -$18.12M | -$21.56M | -$19.02M | -$21.91M | -$22.15M | -$18.62M | -$17.66M | -$15.31M | -$12.24M | -$9.67M | -$8.25M | -$6.63M | -$8M | -$6.72M | -$6.33M | -$5.54M | -$6.3M | -$5.5M | -$4.57M | -$4M | -$3.42M | -$1.43M | -$2.47M | -$3.18M | -$3.14M | -$1.73M | -$857K |
EBITDA | -$105.64M | -$57.17M | -$56.89M | -$61.94M | -$53.57M | -$61.25M | -$55.39M | -$44.15M | -$47.77M | -$49.59M | -$22.79M | $160.31M | -$18.26M | -$18.78M | -$18.25M | -$21.85M | -$24.04M | -$20.03M | -$19.88M | -$6.31M | -$17.85M | -$22.41M | -$17.87M | -$21.34M | -$18.87M | -$21.8M | -$22.04M | -$18.52M | -$17.56M | -$15.23M | -$12.17M | -$9.6M | -$8.18M | -$6.56M | -$7.93M | -$6.66M | -$6.28M | -$5.51M | -$6.27M | -$5.46M | -$4.54M | -$3.97M | -$3.39M | -$1.41M | -$2.45M | -$3.17M | -$3.02M | -$1.06M | -$193K |
